Umama S. Gorsi, MD

Advanced Heart Failure & Transplant Cardiology • University of Cincinnati

Dr. Umama Gorsi is an assistant professor of clinical medicine and an advanced heart failure/transplant cardiologist at the University of Cincinnati. She cares for patients with complex heart failure, cardiomyopathy, mechanical circulatory support, and heart transplantation needs, with a special interest in hypertrophic cardiomyopathy and preventive cardiology.

View Dr. Umama S. Gorsi latest publications for the following journals:

Biography

Dr. Umama S. Gorsi is an Assistant Professor of Clinical Internal Medicine (Cardiology) at the University of Cincinnati College of Medicine and an Attending Cardiologist with UC Health. She specializes in advanced heart failure, cardiogenic shock, mechanical circulatory support (LVAD), heart transplantation, and hypertrophic cardiomyopathy.

Passionate about prevention and patient education, Dr. Gorsi launched preventive cardiology initiatives during her training and continues to integrate lifestyle counseling into daily practice.

She completed her residency in internal medicine, followed by a cardiovascular disease fellowship, advanced subspecialty training in heart failure and transplant cardiology, and additional focused training in preventive cardiology. She is board-certified in Internal Medicine, Cardiovascular Disease, and Advanced Heart Failure & Transplant Cardiology.

At the University of Cincinnati, Dr. Gorsi divides her time between patient care, clinical research, and mentoring residents and fellows. Her academic interests include noninvasive detection of transplant rejection, emerging therapies for hypertrophic cardiomyopathy, and clinical outcomes in heart failure. She is actively involved in multi-center clinical trials, bringing next-generation therapies to patients while teaching the next generation of cardiologists.

Conditions & Services

Dr. Gorsi provides comprehensive care for patients across the spectrum of heart failure and cardiomyopathy, collaborating closely with cardiac surgery, nephrology, and transplant teams.

Conditions Treated

  • Advanced heart failure (HFrEF/HFpEF) and cardiogenic shock
  • Hypertrophic cardiomyopathy (including obstructive HCM)
  • Dilated and genetic cardiomyopathies
  • Pre- and post-heart transplantation care
  • LVAD and temporary mechanical circulatory support
  • Complex hypertension; ischemic and valvular contributors to heart failure

Services Offered

  • Advanced heart failure evaluation and longitudinal management
  • Transplant evaluation, listing, and post-transplant surveillance
  • Mechanical circulatory support (LVAD) assessment and follow-up
  • Hypertrophic cardiomyopathy assessment, medical therapy optimization, and procedural coordination when indicated
  • Preventive cardiology counseling (risk factor modification, rehab coordination)

*Care is delivered in close collaboration with cardiac surgery, nephrology, imaging, and transplant teams to ensure seamless, multidisciplinary support.

Research & Clinical Trials

Dr. Gorsi participates in groundbreaking clinical research to advance treatments for heart failure and cardiomyopathy. Eligible patients may be offered enrollment in active studies, ensuring access to next-generation therapies.

2023–2026

MYK-224 in Obstructive HCM

Bristol Myers Squibb – Site Principal Investigator

A multi-year, industry-sponsored trial evaluating an investigational therapy (MYK-224) in patients with symptomatic obstructive hypertrophic cardiomyopathy.

View Study →
2024–Ongoing

XXB750 in Heart Failure

Novartis – Principal Investigator

A multicenter, placebo-controlled trial of an experimental agent (XXB750) for patients with heart failure, exploring novel therapeutic pathways and improved outcomes.

View Study →

Research Interests

Noninvasive detection of transplant rejection HCM therapeutics & phenotype-guided care Advanced heart failure outcomes Mechanical circulatory support research

Areas of Clinical Focus & Research Specialization

Dr. Umama S. Gorsi’s expertise spans advanced cardiac care, preventive cardiology, and research-driven innovation in heart failure and cardiomyopathy.

Advanced Heart Failure & Transplant Cardiology

Management of patients with advanced heart failure, cardiogenic shock, mechanical circulatory support (LVADs), and heart transplantation. Board certified in Advanced Heart Failure & Transplant Cardiology, she provides comprehensive care for the sickest patients. Learn more ↗

Hypertrophic Cardiomyopathy

As Director of the Hypertrophic Obstructive Cardiomyopathy (HOCM) Clinic, Dr. Gorsi leads specialized care and participates in clinical trials for emerging HOCM therapies. Explore HOCM care ↗

Preventive Cardiology

Passionate about prevention, she founded a Preventive Cardiology Clinic during training and continues to emphasize lifestyle education, risk factor management, and patient empowerment. Preventive care at UC Health ↗

General Cardiovascular Disease

Board certified in Cardiovascular Disease and Internal Medicine, she also provides holistic care for heart failure in all forms and general cardiology conditions. Visit UC College of Medicine ↗

Research Interests

  • Noninvasive detection of heart transplant rejection (advanced echocardiography)
  • Impact of sleep apnea risk factors on heart failure in women
  • Leading clinical trials of novel heart failure & cardiomyopathy therapies

Institutional Affiliations & Current Roles

University of Cincinnati College of Medicine

Assistant Professor of Clinical Medicine (Cardiology) in the Department of Internal Medicine.

UC Health / University of Cincinnati Medical Center

Attending cardiologist specializing in advanced heart failure and transplant care at the University of Cincinnati Medical Center. Member of the advanced heart failure and transplant cardiology team.

Hypertrophic Cardiomyopathy Clinic Director

Leads the HOCM Clinic, overseeing multidisciplinary care and novel treatment strategies for patients with hypertrophic cardiomyopathy.

Areas of Clinical Focus & Research Specialization

Advanced Heart Failure & Transplant

Expertise in managing complex patients with advanced heart failure, cardiogenic shock, mechanical circulatory support devices, and heart transplant needs. Board certified in Advanced Heart Failure & Transplant Cardiology (Sharecare).

Hypertrophic Cardiomyopathy

As HOCM Clinic Director, Dr. Gorsi specializes in hypertrophic obstructive cardiomyopathy, staying at the forefront of emerging therapies and leading clinical trials.

Preventive Cardiology

Passionate about prevention and education. Established a preventive cardiology clinic during training at UC Health, and continues to emphasize risk factor management and healthy lifestyles in her practice.

General Cardiovascular Disease

Board certified in general cardiovascular disease and internal medicine (UC Medicine). Provides comprehensive cardiology care with a holistic approach.

Research Alignment

Research interests align with her clinical expertise in heart failure and cardiomyopathy, including noninvasive transplant rejection detection (advanced echocardiography) and outcomes in women with heart failure. Currently leads multiple ongoing clinical trials in novel heart failure and cardiomyopathy therapies.

Outreach & Contact Insights

Patient Engagement & Communication

Dr. Gorsi provides compassionate, holistic care, always putting patients and families first (UC Health). Having trained across Pakistan and the U.S., she connects with patients from diverse backgrounds. She is multilingual in English, Urdu, and Punjabi, which enhances her ability to engage with immigrant and minority communities.

Community & Preventive Outreach

Through her preventive cardiology initiatives, she has contributed directly to patient outreach and improved health literacy (UC Health). She often emphasizes healthy lifestyle education and may participate in local heart health events and seminars to support her community.

Digital Presence

Active on professional digital platforms, Dr. Gorsi shares insights on innovations in cardiology, such as artificial intelligence applications in the field (Twitter). This strengthens her professional accessibility and promotes patient education online.

Contact & Collaboration

For professional outreach or collaboration, Dr. Gorsi can be contacted via her University of Cincinnati profile.

Email: gorsius@ucmail.uc.edu

Phone: (UC College of Medicine Faculty Office)

She welcomes interdisciplinary collaboration, especially in heart failure, cardiomyopathy, and innovative cardiologic therapies.

📚 Selected Publications

A selection of Dr. Gorsi’s most impactful research contributions in cardiology and related fields.

🫀

Obstructive Sleep Apnea Risk Factors and Incident Heart Failure Subtypes in Postmenopausal Women

Journal of Clinical Sleep Medicine, 2020

🔗 Read Publication
💓

Speckle-Tracking Strain and Systolic Strain Rate to Predict Rejection in Transplant Hearts with Preserved EF

BMC Cardiovascular Disorders, 2018

🔗 Read Publication
🧬

Lyme Carditis Presenting with Complete Heart Block — Diagnosis and Recovery

Case Reports in Cardiology, 2016

🔗 Read Publication
📖

Rectus Sheath Hematoma — An Uncommon Cause of Acute Abdominal Pain

Rhode Island Medical Journal, 2017

🔗 Read Publication

🧾 Patient Guides

Helpful resources prepared by Dr. Gorsi for patients and families navigating heart conditions.

📘 Living Well with Advanced Heart Failure

Diet, sodium, daily weights, activity

⬇ Download

⚙️ LVAD & Transplant: What to Expect

Evaluation to long-term care

⬇ Download

❤️ Understanding Hypertrophic Cardiomyopathy

Symptoms, therapy options

⬇ Download

❓ Patient FAQ

If your heart failure symptoms persist despite medications, or if you’ve had hospitalizations for worsening heart failure, advanced therapies such as LVAD or transplant may be considered.
Rejection is typically monitored through biopsies, imaging, and lab markers, with ongoing follow-up by the transplant team.
Limiting sodium, daily weight checks, medication adherence, and physical activity as tolerated are key lifestyle measures.

🗓 Prepare for Your Visit

Make the most of your appointment by reviewing guides and FAQs beforehand.

Get Started

📍 Contact & Locations

UC Health – Cardiovascular Services
University of Cincinnati Medical Center

Appointments: 513-558-1032

Email: gorsius@ucmail.uc.edu